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St. Charles Riverfront

Construction Begins on St. Charles' Riverpointe

CRG and Clayco have started construction on the first phases of Riverpointe, a $350 million development more than a decade in the making, which, over the next five years, looks to revitalize 120 acres along the Missouri River at Interstate 70 and Main Street, building on the success of the neighboring 27-acre mixed-use development that opened in 2012, The Streets of St. Charles.

St. Louis Arch

“St. Louis Is #1 City to Start Your Career!” – CNBC Report

A new report by CNBC ranks St. Louis as the #1 location in the country for college grads to start a career, besting other cities like New York, San Francisco, Denver, and Nashville.

St. Peters MO

St. Peters Named #22 Best Place To Live

Money Magazine has named the City of St. Peters to its 2021 list of the Best Places to Live in America. St. Peters was the only Missouri city named to the 2021 list.

O'Fallon Ranks at the Top SmartAsset's List of Most Livable Small Cities

St. Charles also cracked the Top 10 coming in at #9.

St. Charles County Among Healthiest in Missouri

For the 13th consecutive year, St. Charles County is recognized by the Robert Wood Johnson Foundation and the University of Wisconsin’s Population Health Institute among the state’s healthiest.

The rankings place St. Charles County among Missouri and the nation’s top performers in many of the evaluated sections.

Katy Trail

Katy Trail State Park has been named the #2 Recreational Trail in the nation in USA Today’s 10 Best Readers’ Choice Awards

Did you know the trailhead for the Katy Trail is in St. Charles County? The portion running through St. Charles County is also some of the most used portion of the trail.  Read more about this year's rankings.

Best Place To Start A Business

St. Charles County Among The Best Places To Start A Business

WalletHub recently released it list of best and worst places to start a business and four St. Charles County (Wentzville, St. Charles, St. Peters, and O'Fallon) rank among the Top 500 of best places to start a business!  More than 1,300 cites were evaluated on their business-friendliness.

St. Louis Zoo

St. Louis Regional Rankings

We know the St. Louis Zoo ranks among the best in the world, but did you know about these other rankings?

Welcome to the St. Charles Regional Chamber

Welcome to the home page of the St. Charles Regional Chamber! We're glad you're here!

Our Mission: We advocate for our business community by developing opportunities and partnerships that strengthen the economic prosperity and sustainability of our region.

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STL Wins $25M Build Back Better Grant!

By speaking with one voice and putting forth one collaborative proposal with input from across the bi-state St. Louis metro, the St. Louis region has succeeded in winning a $25 million highly competitive federal Build Back Better Regional Challenge grant.

Learn More


Through ScholarPath, employers find passionate and prepared students who are a perfect fit for their company.

Chamber Video

Scholarpath Website

New Community Profile Book Released

The St. Charles Regional Chamber has released its latest Community Profile Book featuring St. Charles County. This book is great for businesses and individuals looking to locate to St. Charles County.  Click link below to view online or call the Chamber at 636.946.0633 to have one mailed.

Community Profile Book

Chamber Benefit Plan

The Chamber Benefit Plan is a self-funded medical offering built on the multiple employer welfare arrangement model. This program enables smaller employers to join together to share in the overall claims risk.

Powered by the Missouri Chamber Federation and administered by Anthem Blue Cross and Blue Shield, the Chamber Benefit Plan is available to small group employers in Missouri who have 2 to 50 eligible employees.

Elite Members